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<dc:title xml:lang="fr">Contribution de l'IRM à l'analyse de la physiologie de la déglutition et des dysphagies oropharyngées : étude fonctionnelle des prothèses intra-laryngées</dc:title>
<dcterms:alternative xml:lang="en">Contribution of cine-MRI to the physiology of swallowing and oro-pharyngeal dysphagia : functional study of intra-laryngeal prostheses</dcterms:alternative>
<dc:subject xml:lang="fr">Ciné-IRM</dc:subject>
<dc:subject xml:lang="fr">Dysphagies oropharyngées</dc:subject>
<dc:subject xml:lang="fr">Déglutition salivaire</dc:subject>
<dc:subject xml:lang="fr">D-GRID</dc:subject>
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<dc:subject xml:lang="en">Cine-MRI</dc:subject>
<dc:subject xml:lang="en">Oro-pharyngeal dysphagia</dc:subject>
<dc:subject xml:lang="en">Dry swallowing</dc:subject>
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<dc:subject xml:lang="en">Intra-laryngeal prostheses</dc:subject>
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<tef:elementdEntree autoriteExterne="028188403" autoriteSource="Sudoc">Troubles de la déglutition</tef:elementdEntree>
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<dcterms:abstract xml:lang="fr">Ces travaux ont pour objectif, à partir de l’analyse en ciné-IRM du processus de déglutition salivaire chez un sujet sain, d’optimiser le rendement clinique de cette technique pour les dysphagies. Un protocole d’imagerie rapide et une grille d’évaluation (D-GRID) ont été conçus. Leur application a été étudiée chez des patients présentant une tumeur des voies aéro-digestives supérieures, et chez des patients porteurs de Prothèses Intra-Laryngées (PIL). LaD-GRID permet de mesurer et d’évaluer le mécanisme de protection des voies aériennes, de concevoir des programmes de réhabilitation et de suivre l’évolution des dysphagies. L’analyse de la déglutition en ciné-IRM est limitée par l’absence de bolus et la position de decubitus dorsal, mais nos résultats montrent sa fiabilité. La ciné-IRM définit des modèles du déplacement normal ou anormal des structures anatomiques au cours de la déglutition.Les données de l’imagerie dynamique contribuent au développement des PIL.</dcterms:abstract>
<dcterms:abstract xml:lang="en">The aim of this study was to develop the use of fast imaging to assess the swallowing mechanism in healthy volunteers, and to optimize its clinical use in case of oro-pharyngeal dysphagia. A fast imaging protocol during dry swallowing and an evaluation grid (D-GRID) were designed. Healthy subjects, patients with head and neck canceror patients implanted with intra-laryngeal prostheses under went kinetic MRI. True-FISP sequences provide accurate information about morphological aspects of the oro-pharyngo-larynx and displacements of anatomical structures involved in the normal or impaired swallowing mechanism. The analysis of the swallowing process with cine-MRIis restricted because of the lack of bolus and the supine position, but our outcomes are reliable. Patterns of normal orabnormal anatomical structures movements during swallowing are determined by cine-MRI. The development ofIntra-Laryngeal Prostheses represents a therapeutic solution partly based on dynamic MRI data.</dcterms:abstract>
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