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<dc:title xml:lang="fr">Imagerie de la ventilation par tomodensitométrie double énergie simple source avec inhalation de gaz noble : optimisation du protocole et résultats préliminaires</dc:title>
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<dc:subject xml:lang="fr">Tomodensitométrie</dc:subject>
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<dc:subject xml:lang="fr">Ventilation</dc:subject>
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<dc:subject xml:lang="fr">Irradiation</dc:subject>
<dc:subject xml:lang="fr">Contraste</dc:subject>
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<dc:subject xml:lang="fr">Greffe pulmonaire</dc:subject>
<dc:subject xml:lang="fr">Bronchiolite oblitérante</dc:subject>
<dc:subject xml:lang="en">Computed tomography</dc:subject>
<dc:subject xml:lang="en">Dual Energy</dc:subject>
<dc:subject xml:lang="en">Ventilation</dc:subject>
<dc:subject xml:lang="en">Krypton</dc:subject>
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<dcterms:abstract xml:lang="fr">Ce travail portant sur l’imagerie tomodensitométrique double énergie de la ventilation a permis d’établir les points suivants :• L’irradiation d’un examen thoracique acquis en double énergie peut être abaissée à celle d’un examen acquis en simple énergie, grâce à l’utilisation de la reconstruction itérative.• L’analyse qualitative du parenchyme pulmonaire en imagerie double énergie doit se faire sur les reconstructions monochromatiques 50-55keV.• L’atténuation théorique maximale du Krypton dosé à 80% est modérément inférieure à celle du Xénon dosé à 30%.• La décomposition des matériaux en tomodensitométrie double énergie simple source est possible sur le Xénon et le Krypton.• L’utilisation d’un produit de contraste gazeux n’a pas d’impact significatif sur le Workflow en routine clinique.• Le Krypton est cliniquement sûr à la dose de 80%.• La technique ne permet pas de détecter le Krypton au-delà de la carène de manière satisfaisante, probablement en raison d’une concentration en gaz atteinte insuffisante.• Le recalage élastique augmente les performances diagnostiques de détection de la bronchiolite oblitérante par rapport à une simple analyse visuelle.</dcterms:abstract>
<dcterms:abstract xml:lang="en">This work on dual energy CT ventilation imaging has established the following:• The radiation dose of a dual energy chest CT can be reduced to that of a single energy examination through the use of iterative reconstruction.• The qualitative analysis of the lung parenchyma should be made on the 50-55keV monochromatic reconstructions.• The maximum theoretical attenuation obtained with 80% Krypton is moderately inferior to that of 30% Xenon.• Dual energy material decomposition of Xenon and Krypton is efficient with a single source technique.• The use of a gaseous contrast agent has no significant impact on the workflow in the clinical setting.• The Krypton is safe at 80% concentration.• The technique does not satisfactorily detect Krypton beyond the carina, probably due to insufficient gas concentration.• The elastic registration increases the diagnostic performance of bronchiolitis obliterans syndrome detection, compared to a simple visual analysis.</dcterms:abstract>
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