<?xml version="1.0" encoding="UTF-8"?><mets:mets xmlns:mets="http://www.loc.gov/METS/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:mads="http://www.loc.gov/mads/" xmlns:metsRights="http://cosimo.stanford.edu/sdr/metsrights/" xmlns:suj="http://www.theses.fr/namespace/sujets" xmlns:tef="http://www.abes.fr/abes/documents/tef" xmlns:tefextension="http://www.abes.fr/abes/documents/tefextension" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.loc.gov/METS/ http://www.abes.fr/abes/documents/tef/recommandation/tef_schemas.xsd">
<mets:metsHdr CREATEDATE="2019-09-12T13:03:21" ID="ABES.STAR.THESE_126370.METS_HEADER" LASTMODDATE="2024-04-17T03:43:25Z" RECORDSTATUS="valide">
<mets:agent ROLE="CREATOR">
<mets:name/>
<mets:note>Note</mets:note>
</mets:agent>
<mets:agent ROLE="DISSEMINATOR">
<mets:name>ABES</mets:name>
</mets:agent>
<mets:altRecordID ID="ABES.STAR.THESE_126370.METS_HEADER.ALTERNATE" TYPE=""/>
</mets:metsHdr>
<mets:dmdSec ID="ABES.STAR.THESE_126370.DESCRIPTION_BIBLIOGRAPHIQUE">
<mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_desc_these">
<mets:xmlData>
<tef:thesisRecord>
<dc:title xml:lang="fr">Parallélisation hybride d’une application de détection de noyaux cellulaires</dc:title>
<dcterms:alternative xml:lang="en">Hybrid parallelization of a cell nucleus detection application</dcterms:alternative>
<dc:subject xml:lang="fr">Calcul parallèle hybride</dc:subject>
<dc:subject xml:lang="fr">Imagerie médicale</dc:subject>
<dc:subject xml:lang="fr">Détection automatique de cancer du sein</dc:subject>
<dc:subject xml:lang="en">Hybrid parallel computing</dc:subject>
<dc:subject xml:lang="en">Medical imaging</dc:subject>
<dc:subject xml:lang="en">Automatic breast cancer detection</dc:subject>
<dc:subject xsi:type="dcterms:DDC">006.6</dc:subject>
<dc:subject xsi:type="dcterms:DDC">616.075</dc:subject>
<dc:subject xsi:type="dcterms:DDC">616.99</dc:subject>
<tef:sujetRameau xml:lang="fr">
<tef:vedetteRameauNomCommun>
<tef:elementdEntree autoriteExterne="027248585" autoriteSource="Sudoc">Cancer du sein</tef:elementdEntree>
<tef:subdivision autoriteExterne="031314287" autoriteSource="Sudoc" type="subdivisionDeSujet">Cytodiagnostic</tef:subdivision>
</tef:vedetteRameauNomCommun>
<tef:vedetteRameauNomCommun>
<tef:elementdEntree autoriteExterne="035571314" autoriteSource="Sudoc">Algorithmes parallèles</tef:elementdEntree>
</tef:vedetteRameauNomCommun>
<tef:vedetteRameauNomCommun>
<tef:elementdEntree autoriteExterne="032043465" autoriteSource="Sudoc">Télédiagnostic</tef:elementdEntree>
</tef:vedetteRameauNomCommun>
<tef:vedetteRameauNomCommun>
<tef:elementdEntree autoriteExterne="027577716" autoriteSource="Sudoc">Imagerie médicale</tef:elementdEntree>
</tef:vedetteRameauNomCommun>
</tef:sujetRameau>
<dcterms:abstract xml:lang="fr">L’algorithme Marked Point Process parallélisé en mémoire partagée permet d’accélérer la détection de noyaux cellulaires. Cependant, les limites imposées par le nombre de cœurs CPU ou la capacité mémoire des cartes GPU ne permet pas d’analyser une image histologique entière (50 000 × 50 000 pixels). Pour y parvenir, nous proposons d’ajouter une dimension distribuée à cette parallélisation en utilisant le modèle hybride Ordered Read-Write Locks. Afin de garantir la validité de l’algorithme original, nous avons mis en place différentes stratégies pour d’une part garantir le traitement de l’ensemble des noyaux et d’autre part, pour que les traitements locaux soient considérés à l’échelle globale. Les tests menés ont tout d’abord permis de valider le passage à l’échelle de l’application puis d’afficher un facteur d’accélération de 40 sur 64 cœurs CPU.</dcterms:abstract>
<dcterms:abstract xml:lang="en">The shared memory parallelized version of the Marked Point Process algorithm allows to speed-up cells nuclei detection. However, the limitations imposed by the number of CPU cores or the memory capacity of GPU cards do not allow to analyse an entire histological image (50,000 × 50,000 pixels). To achieve this, we propose to add a distributed dimension to this parallelization using the hybrid Ordered Read-Write Locks model. In order to guarantee the validity of the original algorithm, we have implemented different strategies to ensure that all nuclei are processed and that local processing is considered on a global scale. The tests carried out first validated the scalability of the application and then showed an acceleration factor of 40 on 64 CPU cores.</dcterms:abstract>
<dc:type>Electronic Thesis or Dissertation</dc:type>
<dc:type xsi:type="dcterms:DCMIType">Text</dc:type>
<dc:language xsi:type="dcterms:RFC3066">fr</dc:language>
</tef:thesisRecord>
</mets:xmlData>
</mets:mdWrap>
</mets:dmdSec>
<mets:dmdSec ID="ABES.STAR.THESE_126370.VERSION_COMPLETE.DESCRIPTION.EDITION_ARCHIVAGE">
<mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_desc_edition">
<mets:xmlData>
<tef:edition>
<dcterms:medium xsi:type="dcterms:IMT">PDF</dcterms:medium>
<dcterms:extent>41683778</dcterms:extent>
<tef:editeur>
<tef:nom>Université de Strasbourg</tef:nom>
<tef:place>Strasbourg</tef:place>
</tef:editeur>
<dcterms:issued xsi:type="dcterms:W3CDTF">2019-12-31</dcterms:issued>
<dc:identifier xsi:type="dcterms:URI">https://theses.hal.science/tel-02511544</dc:identifier>
</tef:edition>
</mets:xmlData>
</mets:mdWrap>
</mets:dmdSec>
<mets:dmdSec ID="ABES.STAR.THESE_126370.VERSION_COMPLETE.DESCRIPTION.EDITION_1">
<mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_desc_edition">
<mets:xmlData>
<tef:edition>
<dcterms:medium xsi:type="dcterms:IMT">application/pdf</dcterms:medium>
<dcterms:extent>2662707</dcterms:extent>
<dc:identifier xsi:type="dcterms:URI">https://publication-theses.unistra.fr/public/theses_doctorat/2019/Salas_Daniel_2019_ED269.pdf</dc:identifier>
<dc:identifier xsi:type="dcterms:URI">http://www.theses.fr/2019STRAD018/abes</dc:identifier>
<dc:identifier xsi:type="dcterms:URI"/>
<dc:identifier xsi:type="dcterms:URI">https://theses.hal.science/tel-02511544</dc:identifier>
<dc:identifier xsi:type="dcterms:URI">https://theses.hal.science/tel-02511544</dc:identifier>
<dc:identifier xsi:type="dcterms:URI">https://theses.hal.science/tel-02511544</dc:identifier>
</tef:edition>
</mets:xmlData>
</mets:mdWrap>
</mets:dmdSec>
<mets:amdSec>
<mets:techMD ID="ABES.STAR.THESE_126370.ADMINISTRATION">
<mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_admin_these">
<mets:xmlData>
<tef:thesisAdmin>
<tef:auteur>
<tef:nom>Salas</tef:nom>
<tef:prenom>Daniel</tef:prenom>
<tef:dateNaissance>1976-04-27</tef:dateNaissance>
<tef:nationalite scheme="ISO-3166-1">FR</tef:nationalite>
<tef:autoriteExterne autoriteSource="Sudoc">243004451</tef:autoriteExterne>
</tef:auteur>
<dc:identifier xsi:type="tef:nationalThesisPID">https://theses.fr/2019STRAD018</dc:identifier>
<dc:identifier xsi:type="tef:NNT">2019STRAD018</dc:identifier>
<dc:identifier xsi:type="tef:DOI">https://doi.org/10.70675/dc5b9220z506dz427cz816dz80b2048774a8</dc:identifier>
<dcterms:dateAccepted xsi:type="dcterms:W3CDTF">2019-09-10</dcterms:dateAccepted>
<tef:thesis.degree>
<tef:thesis.degree.discipline xml:lang="fr">Informatique</tef:thesis.degree.discipline>
<tef:thesis.degree.grantor>
<tef:nom>Strasbourg</tef:nom>
<tef:autoriteExterne autoriteSource="Sudoc">131056549</tef:autoriteExterne>
</tef:thesis.degree.grantor>
<tef:thesis.degree.level>Doctorat</tef:thesis.degree.level>
<tef:thesis.degree.name xml:lang="fr">Docteur es</tef:thesis.degree.name>
</tef:thesis.degree>
<tef:theseSurTravaux>non</tef:theseSurTravaux>
<tef:avisJury>oui</tef:avisJury>
<tef:directeurThese>
<tef:nom>Gustedt</tef:nom>
<tef:prenom>Jens</tef:prenom>
<tef:autoriteInterne>MADS_DIRECTEUR_DE_THESE_1</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">077834437</tef:autoriteExterne>
</tef:directeurThese>
<tef:presidentJury>
<tef:nom>Emad Petiton</tef:nom>
<tef:prenom>Nahid</tef:prenom>
<tef:autoriteInterne>MADS_PRESIDENT_DU_JURY</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">098461575</tef:autoriteExterne>
</tef:presidentJury>
<tef:membreJury>
<tef:nom>Gustedt</tef:nom>
<tef:prenom>Jens</tef:prenom>
<tef:autoriteInterne>MADS_MEMBRE_DU_JURY_1</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">077834437</tef:autoriteExterne>
</tef:membreJury>
<tef:membreJury>
<tef:nom>Emad Petiton</tef:nom>
<tef:prenom>Nahid</tef:prenom>
<tef:autoriteInterne>MADS_MEMBRE_DU_JURY_2</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">098461575</tef:autoriteExterne>
</tef:membreJury>
<tef:membreJury>
<tef:nom>Breton</tef:nom>
<tef:prenom>Vincent</tef:prenom>
<tef:autoriteInterne>MADS_MEMBRE_DU_JURY_3</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">138522189</tef:autoriteExterne>
</tef:membreJury>
<tef:membreJury>
<tef:nom>Perseil</tef:nom>
<tef:prenom>Isabelle</tef:prenom>
<tef:autoriteInterne>MADS_MEMBRE_DU_JURY_4</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">159775922</tef:autoriteExterne>
</tef:membreJury>
<tef:membreJury>
<tef:nom>Noblet</tef:nom>
<tef:prenom>Vincent</tef:prenom>
<tef:autoriteInterne>MADS_MEMBRE_DU_JURY_5</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">115580166</tef:autoriteExterne>
</tef:membreJury>
<tef:membreJury>
<tef:nom>Kern</tef:nom>
<tef:prenom>Michel</tef:prenom>
<tef:autoriteInterne>MADS_MEMBRE_DU_JURY_6</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">032716079</tef:autoriteExterne>
</tef:membreJury>
<tef:rapporteur>
<tef:nom>Emad Petiton</tef:nom>
<tef:prenom>Nahid</tef:prenom>
<tef:autoriteInterne>MADS_RAPPORTEUR_1</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">098461575</tef:autoriteExterne>
</tef:rapporteur>
<tef:rapporteur>
<tef:nom>Breton</tef:nom>
<tef:prenom>Vincent</tef:prenom>
<tef:autoriteInterne>MADS_RAPPORTEUR_2</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">138522189</tef:autoriteExterne>
</tef:rapporteur>
<tef:ecoleDoctorale>
<tef:nom>École doctorale Mathématiques, sciences de l'information et de l'ingénieur (Strasbourg ; 1997-....)</tef:nom>
<tef:autoriteInterne>MADS_ECOLE_DOCTORALE_1</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">156504863</tef:autoriteExterne>
</tef:ecoleDoctorale>
<tef:partenaireRecherche type="laboratoire">
<tef:nom>Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (Strasbourg ; 2013-....)</tef:nom>
<tef:autoriteInterne>MADS_PARTENAIRE_DE_RECHERCHE_1</tef:autoriteInterne>
<tef:autoriteExterne autoriteSource="Sudoc">176969721</tef:autoriteExterne>
<tef:autoriteExterne autoriteSource="labTEL">260728</tef:autoriteExterne>
</tef:partenaireRecherche>
<tef:oaiSetSpec>ddc:004</tef:oaiSetSpec>
<tef:oaiSetSpec>ddc:610</tef:oaiSetSpec>
<tef:MADSAuthority authorityID="MADS_DIRECTEUR_DE_THESE_1" type="personal">
<tef:personMADS>
<mads:namePart type="family">Gustedt</mads:namePart>
<mads:namePart type="given">Jens</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_PRESIDENT_DU_JURY" type="personal">
<tef:personMADS>
<mads:namePart type="family">Emad Petiton</mads:namePart>
<mads:namePart type="given">Nahid</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_MEMBRE_DU_JURY_1" type="personal">
<tef:personMADS>
<mads:namePart type="family">Gustedt</mads:namePart>
<mads:namePart type="given">Jens</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_MEMBRE_DU_JURY_2" type="personal">
<tef:personMADS>
<mads:namePart type="family">Emad Petiton</mads:namePart>
<mads:namePart type="given">Nahid</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_MEMBRE_DU_JURY_3" type="personal">
<tef:personMADS>
<mads:namePart type="family">Breton</mads:namePart>
<mads:namePart type="given">Vincent</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_MEMBRE_DU_JURY_4" type="personal">
<tef:personMADS>
<mads:namePart type="family">Perseil</mads:namePart>
<mads:namePart type="given">Isabelle</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_MEMBRE_DU_JURY_5" type="personal">
<tef:personMADS>
<mads:namePart type="family">Noblet</mads:namePart>
<mads:namePart type="given">Vincent</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_MEMBRE_DU_JURY_6" type="personal">
<tef:personMADS>
<mads:namePart type="family">Kern</mads:namePart>
<mads:namePart type="given">Michel</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_RAPPORTEUR_1" type="personal">
<tef:personMADS>
<mads:namePart type="family">Emad Petiton</mads:namePart>
<mads:namePart type="given">Nahid</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_RAPPORTEUR_2" type="personal">
<tef:personMADS>
<mads:namePart type="family">Breton</mads:namePart>
<mads:namePart type="given">Vincent</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_ECOLE_DOCTORALE_1" type="corporate">
<tef:personMADS>
<mads:namePart type="family">École doctorale Mathématiques, sciences de l'information et de l'ingénieur (Strasbourg ; 1997-....)</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
<tef:MADSAuthority authorityID="MADS_PARTENAIRE_DE_RECHERCHE_1" type="corporate">
<tef:personMADS>
<mads:namePart type="family">Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (Strasbourg)</mads:namePart>
</tef:personMADS>
</tef:MADSAuthority>
</tef:thesisAdmin>
</mets:xmlData>
</mets:mdWrap>
</mets:techMD>
<mets:techMD ID="ABES.STAR.THESE_126370.VERSION_COMPLETE.EDITION_ARCHIVAGE.TECH_FICHIER.DOSSIER_1.DOSSIER_1.FICHIER_1">
<mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_tech_fichier">
<mets:xmlData>
<tef:meta_fichier>
<tef:formatFichier>PDF</tef:formatFichier>
<tef:taille>41683778</tef:taille>
</tef:meta_fichier>
</mets:xmlData>
</mets:mdWrap>
</mets:techMD>
<mets:rightsMD ID="ABES.STAR.THESE_126370.DROITS_UNIVERSITE">
<mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_droits_etablissement_these">
<mets:xmlData>
<metsRights:RightsDeclarationMD RIGHTSCATEGORY="CONTRACTUAL">
<metsRights:Context CONTEXTCLASS="GENERAL PUBLIC">
<metsRights:Permissions COPY="false" DELETE="false" DISPLAY="true" DUPLICATE="true" MODIFY="false" PRINT="false"/>
</metsRights:Context>
<metsRights:Context CONTEXTCLASS="INSTITUTIONAL AFFILIATE">
<metsRights:Permissions COPY="false" DELETE="false" DISPLAY="true" DUPLICATE="true" MODIFY="false" PRINT="false"/>
</metsRights:Context>
</metsRights:RightsDeclarationMD>
</mets:xmlData>
</mets:mdWrap>
</mets:rightsMD>
<mets:rightsMD ID="ABES.STAR.THESE_126370.DROITS_DOCTORANT">
<mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_droits_auteur_these">
<mets:xmlData>
<metsRights:RightsDeclarationMD RIGHTSCATEGORY="CONTRACTUAL">
<metsRights:Context CONTEXTCLASS="GENERAL PUBLIC">
<metsRights:Permissions COPY="false" DELETE="false" DISPLAY="true" DUPLICATE="true" MODIFY="false" PRINT="false"/>
</metsRights:Context>
<metsRights:Context CONTEXTCLASS="INSTITUTIONAL AFFILIATE">
<metsRights:Permissions COPY="false" DELETE="false" DISPLAY="true" DUPLICATE="true" MODIFY="false" PRINT="false"/>
</metsRights:Context>
</metsRights:RightsDeclarationMD>
</mets:xmlData>
</mets:mdWrap>
</mets:rightsMD>
<mets:rightsMD ID="ABES.STAR.THESE_126370.VERSION_COMPLETE.DROITS">
<mets:mdWrap MDTYPE="OTHER" OTHERMDTYPE="tef_droits_version">
<mets:xmlData>
<metsRights:RightsDeclarationMD RIGHTSCATEGORY="CONTRACTUAL">
<metsRights:Context CONTEXTCLASS="GENERAL PUBLIC">
<metsRights:Permissions COPY="false" DELETE="false" DISPLAY="true" DUPLICATE="true" MODIFY="false" PRINT="false"/>
</metsRights:Context>
<metsRights:Context CONTEXTCLASS="INSTITUTIONAL AFFILIATE">
<metsRights:Permissions COPY="false" DELETE="false" DISPLAY="true" DUPLICATE="true" MODIFY="false" PRINT="false"/>
</metsRights:Context>
</metsRights:RightsDeclarationMD>
</mets:xmlData>
</mets:mdWrap>
</mets:rightsMD>
</mets:amdSec>
<mets:fileSec>
<mets:fileGrp ID="ABES.STAR.THESE_126370.VERSION_COMPLETE.EDITION_ARCHIVAGE.FILEGRP" USE="archive">
<mets:file ADMID="ABES.STAR.THESE_126370.VERSION_COMPLETE.EDITION_ARCHIVAGE.TECH_FICHIER.DOSSIER_1.DOSSIER_1.FICHIER_1" ID="ABES.STAR.THESE_126370.VERSION_COMPLETE.EDITION_ARCHIVAGE.DOSSIER_1.DOSSIER_1.FICHIER_1" SEQ="1">
<mets:FLocat LOCTYPE="URL" xlink:href="STRA/THESE_126370/document/0/0/Salas_Daniel_2019_ED269_A.pdf"/>
</mets:file>
</mets:fileGrp>
</mets:fileSec>
<mets:structMap TYPE="logical">
<mets:div ADMID="ABES.STAR.THESE_126370.ADMINISTRATION ABES.STAR.THESE_126370.DROITS_UNIVERSITE ABES.STAR.THESE_126370.DROITS_DOCTORANT" CONTENTIDS="CONTENTIDS.ABES.STAR.THESE_126370" DMDID="ABES.STAR.THESE_126370.DESCRIPTION_BIBLIOGRAPHIQUE" TYPE="THESE">
<mets:div ADMID="ABES.STAR.THESE_126370.VERSION_COMPLETE.DROITS" CONTENTIDS="CONTENTIDS.ABES.STAR.THESE_126370.ABES.STAR.THESE_126370.VERSION_COMPLETE" TYPE="VERSION_COMPLETE">
<mets:div CONTENTIDS="CONTENTIDS.ABES.STAR.THESE_126370.VERSION_COMPLETE.EDITION_ARCHIVAGE" DMDID="ABES.STAR.THESE_126370.VERSION_COMPLETE.DESCRIPTION.EDITION_ARCHIVAGE" TYPE="EDITION">
<mets:fptr FILEID="ABES.STAR.THESE_126370.VERSION_COMPLETE.EDITION_ARCHIVAGE.FILEGRP"/>
</mets:div>
<mets:div CONTENTIDS="CONTENTIDS.ABES.STAR.THESE_126370.VERSION_COMPLETE.EDITION_1" DMDID="ABES.STAR.THESE_126370.VERSION_COMPLETE.DESCRIPTION.EDITION_1" TYPE="EDITION"/>
</mets:div>
</mets:div>
</mets:structMap>
</mets:mets>