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<dc:title xml:lang="fr">Faisabilité et comparaison d'un entrainement aérobie de type continu ou intermittent sur les capacités physiologiques, cognitives et la qualité de vie, chez des personnes âgées présentant un trouble neurocognitif majeur associé à la maladie d'Alzheimer</dc:title>
<dcterms:alternative xml:lang="en">Feasibility and comparison of continuous aerobic training or interval aerobic training on physiological capacities, cognitive capacities and quality of life in aging with dementia associated at Alzheimer’s diseases</dcterms:alternative>
<dc:subject xml:lang="fr">Entrainement aérobie</dc:subject>
<dc:subject xml:lang="fr">Entrainement continu</dc:subject>
<dc:subject xml:lang="fr">Entrainement intermittent</dc:subject>
<dc:subject xml:lang="fr">Endurance cardiorespiratoire</dc:subject>
<dc:subject xml:lang="fr">Capacité cognitive</dc:subject>
<dc:subject xml:lang="fr">BDNF</dc:subject>
<dc:subject xml:lang="fr">Qualité de vie</dc:subject>
<dc:subject xml:lang="fr">Alzheimer</dc:subject>
<dc:subject xml:lang="en">Aerobic training</dc:subject>
<dc:subject xml:lang="en">Continuous training</dc:subject>
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<dc:subject xml:lang="en">Aerobic fitness</dc:subject>
<dc:subject xml:lang="en">Cognitive capacity</dc:subject>
<dc:subject xml:lang="en">Quality of life</dc:subject>
<dc:subject xml:lang="en">Alzheimer disease</dc:subject>
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<dcterms:abstract xml:lang="fr">L’entrainement aérobie (EA) montre des bénéfices sur la santé des personnes âgées présentant la maladie d’Alzheimer (MA) mais les mécanismes physiologiques expliquant ceux-ci restent à analyser. Les objectifs de ce travail étaient d’étudier la faisabilité d’un EA de type continu (EATC) ou intermittent (EATI) durant 9 semaines et de comparer leur effet sur : la synthèse plasmatique du facteur neurotrophique dérivé du cerveau (BDNFp), l’endurance cardiorespiratoire (EC), les capacités cognitives et la qualité de vie (QdV), chez des personnes âgées présentant la MA. Après EATC et EATI, aucun effet n’a été observé sur le taux de BDNFp et les performances cognitives. Une amélioration des paramètres d’endurance a été trouvée. La QdV était améliorée après EATC. Ce travail a montré que l’EATC et l’EATI sont faisables et efficaces indifféremment pour améliorer l’EC. L’EATC a eu un impact positif sur la QdV, mais les 2 types d’EA n’ont pas eu d’effet sur la synthèse de BDNFp et les capacités cognitives.</dcterms:abstract>
<dcterms:abstract xml:lang="en">Aerobic training (AT) shows health benefits for older with Alzheimer disease, but the physiological mechanisms that explain these remain to be analyzed. The objectives of this work were to study the feasibility of continuous aerobic training (CAT) or interval aerobic training (IAT) over 9 weeks and to compare their effect on brain derived neurotrophic factor (BDNF) plasma level, aerobic fitness, cognitive capacities and quality of life (QoL) in older with AD. No significant changes in terms of BDNF plasma level and cognitive performance was measured but a significantly improvement of endurance parameters was found. QoL was improved after CAT. This work shown that CAT and IAT are both feasible and equally effective to improve aerobic fitness. CAT had a positive impact on QoL, but both aerobic training failed to induce significant BDNF responses and improve cognitive performances.</dcterms:abstract>
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