<?xml version="1.0" encoding="UTF-8"?>
<oaidc:dc xmlns:oaidc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:dc="http://purl.org/dc/elements/1.1/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
<dc:coverage xsi:type="unistra:Coverage">FR</dc:coverage>
<dc:creator xsi:type="unistra:Auteur">Scheeck, Morgane</dc:creator>
<dc:date xsi:type="unistra:Date">2023-05-12</dc:date>
<dc:description xsi:type="unistra:Discipline" xml:langue="fre">Pharmacie</dc:description>
<dc:description xsi:type="unistra:Resume" xml:langue="fre">Bien que cliniquement rencontrée il y a plus de 4 millénaires, l'endométriose demeure méconnue, sous-diagnostiquée et inadéquatement prise en charge. Les comités de recherche scientifique mondiaux n'ont pas encore élucidé l'ensemble des "mystères" concernant son étiologie, sa physiopathologie et son histoire naturelle. Au cours de ce mémoire, je présenterai dans un premier temps l'état des connaissances actuelles de l'endométriose (épidémiologie, théories cellulaires et mécanismes impliqués dans sa physiopathologie), étape indispensable pour comprendre l'intérêt des traitements médicamenteux non spécifiques actuellement prescrits. Dans un second temps, nous évoquerons les techniques de diagnostic disponibles), pour enfin nous intéresser aux nouveaux traitements en cours d'études (essais cliniques).</dc:description>
<dc:description xsi:type="unistra:Resume" xml:langue="fre">Althought clinically encountered more than 4 millennia ago, endometriosis remains misunderstood, under-diagnosed and inadequately managed. The world's scientific research committees have not yet elucidated all the "mysteries" concerning its etiology, pathophysiology and natural history. In this dissertation, I will first present the current state of knowledge of endometriosis (epidemiology, cellular theoris and mechanisms involved in its physiopathology), wich is essential to understand the interest of the non-specific drug treatments currently prescribed. Secondly, we will discussthe diagnostic techniques available (and soon to be available), and finally we will look at the new treatments currently being studied (clinical trials).</dc:description>
<dc:format xsi:type="dcterms:IMT">PDF</dc:format>
<dc:rights xsi:type="unistra:Droits" xml:lang="fre">Accès libre</dc:rights>
<dc:identifier xsi:type="dcterms:URI">https://publication-theses.unistra.fr/public/theses_exercice/PHA/2023/2023_SCHEECK_Morgane.pdf</dc:identifier>
<dc:language xsi:type="dcterms:ISO639-2">fr</dc:language>
<dc:publisher xsi:type="unistra:Composante">Faculté de pharmacie</dc:publisher>
<dc:source xsi:type="dcterms:URI">http://www.sudoc.fr/270499245</dc:source>
<dc:subject xml:langue="fre">Endométriose</dc:subject>
<dc:subject xml:langue="fre">Pharmacie Recherche</dc:subject>
<dc:subject xml:langue="fre">Endométriose</dc:subject>
<dc:subject xml:langue="fre">Physiopathologie</dc:subject>
<dc:subject xml:langue="fre">Diagnostic</dc:subject>
<dc:subject xml:langue="fre">Traitements</dc:subject>
<dc:subject xml:langue="fre">Hormonothérapie</dc:subject>
<dc:subject xml:langue="fre">Recherche</dc:subject>
<dc:subject xml:langue="fre">Essais cliniques</dc:subject>
<dc:subject xml:langue="fre">Endometriosis</dc:subject>
<dc:subject xml:langue="fre">Physiopathology</dc:subject>
<dc:subject xml:langue="fre">Diagnosis</dc:subject>
<dc:subject xml:langue="fre">Treatments</dc:subject>
<dc:subject xml:langue="fre">Hormonotherapy</dc:subject>
<dc:subject xml:langue="fre">Research</dc:subject>
<dc:subject xml:langue="fre">Clinical trials</dc:subject>
<dc:subject xml:langue="fre">615</dc:subject>
<dc:title xsi:type="unistra:Titre" xml:lang="fre">Endométriose, nouveaux traitements:comment la recherche avance sur le sujet ?</dc:title>
<dc:type xsi:type="unistra:Mention">Thèse d'exercice</dc:type>
<dc:contributor xsi:type="unistra:Directeur">Marcella De Giorgi</dc:contributor>
<dc:type xsi:type="unistra:TheseExercice">These d'exercice Unistra</dc:type>
</oaidc:dc>
